By eliminating or drastically reducing the need for solvents, mechanochemical processes inherently minimize waste generation, simplify downstream purification, and align closely with the principles of green chemistry. Despite significant advances, the adoption of mechanochemistry in the pharmaceutical industry remains limited. Key barriers include challenges related to scalability, process robustness, economic viability, and compatibility with existing regulatory frameworks.
To unlock the full industrial potential of mechanochemistry, continued innovation in scalable instrumentation and process design is essential. This webinar will introduce the basic concepts of mechanochemistry, providing an overview of different reactor/milling techniques with a strong focus on scalable technologies, including reactive extrusion.
In addition to a coverage of literature examples, a recent case study on amidation reactions performed on kg scale using continuous bead milling will be presented. Safety aspects and energy considerations will also be discussed.
The webinar will be presented by Prof. C. Oliver Kappe from Research Center Pharmaceutical Engineering (RCPE) and University of Graz. It will take place at the following time:
15.00 GMT (UK, Lisbon)
16.00 CET (Paris, Madrid, Frankfurt etc)
10.00 ET (New York, Boston)
7.00 PT (San Francisco, LA)
If you are unable to attend on the day, do not worry, all registrants will be sent links to the recorded session and slides presented afterwards. Registrants who attend the 鈥榣ive鈥� session will receive an e-Certificate of Attendance.
To unlock the full industrial potential of mechanochemistry, continued innovation in scalable instrumentation and process design is essential. This webinar will introduce the basic concepts of mechanochemistry, providing an overview of different reactor/milling techniques with a strong focus on scalable technologies, including reactive extrusion.
In addition to a coverage of literature examples, a recent case study on amidation reactions performed on kg scale using continuous bead milling will be presented. Safety aspects and energy considerations will also be discussed.
The webinar will be presented by Prof. C. Oliver Kappe from Research Center Pharmaceutical Engineering (RCPE) and University of Graz. It will take place at the following time:
15.00 GMT (UK, Lisbon)
16.00 CET (Paris, Madrid, Frankfurt etc)
10.00 ET (New York, Boston)
7.00 PT (San Francisco, LA)
If you are unable to attend on the day, do not worry, all registrants will be sent links to the recorded session and slides presented afterwards. Registrants who attend the 鈥榣ive鈥� session will receive an e-Certificate of Attendance.
