This webinar will help you understand the link as well as differences between apoptosis and necroptosis. It will also introduce new tools developed to activate effectors of necroptosis. A live Q&A session with attendees will follow the presentation.
Topics to be covered:
- Necroptosis is a non-apoptotic from of programmed cell death, which depends on the activity of the kinases RIPK1 and RIPK3
- Apoptosis and necroptosis are functionally linked: enzymes involved in inducing apoptosis, such as caspase-8 and FADD, act to suppress necroptosis
- New tools to directly activate the necroptotic effectors RIPK3 and MLKL
- We find that while RIPK1 activates RIPK3 downstream of receptor signaling by using these tools, it is a key suppressor of RIPK3 activation at steady-state
Register online to receive your login details.
Topics to be covered:
- Necroptosis is a non-apoptotic from of programmed cell death, which depends on the activity of the kinases RIPK1 and RIPK3
- Apoptosis and necroptosis are functionally linked: enzymes involved in inducing apoptosis, such as caspase-8 and FADD, act to suppress necroptosis
- New tools to directly activate the necroptotic effectors RIPK3 and MLKL
- We find that while RIPK1 activates RIPK3 downstream of receptor signaling by using these tools, it is a key suppressor of RIPK3 activation at steady-state
Register online to receive your login details.
