Event
BMCS 3rd Conformational Design in Drug Discovery
Dates
Monday 2nd March 2026 – Save the Date!
Place
GSK Conference Centre, Stevenage, UK
Gunnels Wood Road
Stevenage
Hertfordshire
SG1 2FX
Synopsis
Conformational Design plays a key role in the medicinal chemistry of small molecule drug candidates. The emergence of generative AI models to assist molecular design and free-energy-perturbation techniques critically depend on accurate prediction of 3D ligand conformations. Here we bring together cutting-edge computational methods with experimental free ligand NMR solution conformations and protein-ligand X-ray and CryoEM structures to craft the medicines of tomorrow. We will discuss ligand rigidification and physicochemical optimisation strategies for protein-protein interaction inhibitors, PROTACs, molecular glues, antibody-drug-conjugate payloads and other new modalities. This ·¬ÇÑÉçÇø-BMCS event aims at building a community that shares conformational design strategies, technologies, and successful case studies. It will complement other rational drug design events and promote more successful research into future medicines.
Who should attend?
This symposium will provide great learnings for medicinal chemists, computational chemists, structural biologists, biophysicists and NMR analytical chemists with an academic or industry interest in drug discovery. Prior knowledge in conformational design will not be required.
Registration
·¬ÇÑÉçÇø Member: £125.00
Non-Member: £175.00
·¬ÇÑÉçÇø Student Member: £50.00
Student Non-Member: £70.00
Abstracts
Abstract submission is open for poster and oral presentations. The deadline for abstract submission is Midnight GMT, Friday 12 December, 2025. Please use the following link to submit your abstract: https://hg3.co.uk/cdidd/
Sponsorship/Exhibition Opportunities
Conference Exhibition Stand Package (£900.00)
– A table and chairs
– Logo inclusion in the delegate handbook and rolling slides
– Exhibitors promotional page in the pdf delegate handbook
– Access to the Scientific talks
– Two stand personnel
Organising Committee
Markus Schade, AstraZeneca (Chair)
Martin Swarbrick (Treasurer)
Luca Carlino, AstraZeneca
Tim Barrett, GSK
A. Ganesan, University of East Anglia
Hannah Bruce Macdonald, Isomorphic Labs
BMCS 3rd Conformational Design in Drug Discovery
Dates
Monday 2nd March 2026 – Save the Date!
Place
GSK Conference Centre, Stevenage, UK
Gunnels Wood Road
Stevenage
Hertfordshire
SG1 2FX
Synopsis
Conformational Design plays a key role in the medicinal chemistry of small molecule drug candidates. The emergence of generative AI models to assist molecular design and free-energy-perturbation techniques critically depend on accurate prediction of 3D ligand conformations. Here we bring together cutting-edge computational methods with experimental free ligand NMR solution conformations and protein-ligand X-ray and CryoEM structures to craft the medicines of tomorrow. We will discuss ligand rigidification and physicochemical optimisation strategies for protein-protein interaction inhibitors, PROTACs, molecular glues, antibody-drug-conjugate payloads and other new modalities. This ·¬ÇÑÉçÇø-BMCS event aims at building a community that shares conformational design strategies, technologies, and successful case studies. It will complement other rational drug design events and promote more successful research into future medicines.
Who should attend?
This symposium will provide great learnings for medicinal chemists, computational chemists, structural biologists, biophysicists and NMR analytical chemists with an academic or industry interest in drug discovery. Prior knowledge in conformational design will not be required.
Registration
·¬ÇÑÉçÇø Member: £125.00
Non-Member: £175.00
·¬ÇÑÉçÇø Student Member: £50.00
Student Non-Member: £70.00
Abstracts
Abstract submission is open for poster and oral presentations. The deadline for abstract submission is Midnight GMT, Friday 12 December, 2025. Please use the following link to submit your abstract: https://hg3.co.uk/cdidd/
Sponsorship/Exhibition Opportunities
Conference Exhibition Stand Package (£900.00)
– A table and chairs
– Logo inclusion in the delegate handbook and rolling slides
– Exhibitors promotional page in the pdf delegate handbook
– Access to the Scientific talks
– Two stand personnel
Organising Committee
Markus Schade, AstraZeneca (Chair)
Martin Swarbrick (Treasurer)
Luca Carlino, AstraZeneca
Tim Barrett, GSK
A. Ganesan, University of East Anglia
Hannah Bruce Macdonald, Isomorphic Labs
