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Barcelona Blood-Brain Barrier Conference – B4 2026

3 November 2026 08:00 - 5 November 2026 18:00, Barcelona, Spain


Introduction
The blood-brain barrier (BBB) separates the blood circulation from the brain tissue. However, despite its name, the BBB is far from a static, impenetrable barrier. Instead, this highly dynamic structure responds to and regulates the complex requirements of brain function. To advance our knowledge of how the BBB impacts health and disease, the 3rd edition of the Barcelona Blood-Brain Barrier Conference will bring together scientists from across the globe to discuss emerging topics in BBB physiology, pathology and translational research. This interdisciplinary event will incorporate neuroscience, vascular biology, protein engineering, bioengineering, and nanomedicine to provide a unique platform to foster collaboration and address challenges shaping the future of this field.

In the name of the Institute for Bioengineering of Catalonia (IBEC) and the Institut Químic de Sarrià (IQS), we look forward to welcoming you to the vibrant and historic city of Barcelona to take part in these lively discussions, make lasting connections, and push the boundaries of the field forward.

TOPICS:

Physiology of the BBB

Pericyte and Glial Control of BBB Function
Tight-junction Biology
Endothelial Membrane Dynamics
Mechanobiology at the BBB
Glycocalyx Contributions
Neurovascular Coupling Mechanisms
Circadian Control of BBB Function
Sex Differences at the BBB

The BBB in Disease

BBB Dysfunction in Aging and Cognitive Decline
Neurodegeneration Mechanisms Driven by BBB Dysfunction
The BBB in Brain Cancers: Corrupting the Vasculature
The BBB in Stroke: Novel Concepts and Treatment Strategies
Pathological Angiogenesis and BBB Dysfunction
Immune-BBB crosstalk: Neuroinflammation and Infection
The BBB in Epilepsy and Traumatic Brain Injury
The Role of the BBB in Neuropsychiatric Disorders
Clinical Aspects

Therapeutic Delivery Across the BBB

Nanoparticles for therapeutic brain delivery
Novel brain-targeting strategies
Transcytosis dynamics across the BBB
Advances in Brain Shuttles for BioTherapeutics
Gene Delivery to the BBB and the Brain Parenchyma
Strategies to Transiently Open the BBB

Modelling, Imaging and Omics of the BBB

Advances in Imaging Techniques to Study BBB Dynamics
Advanced Bioengineering Models of the BBB
Omics and Computational Modeling of the BBB
Stem-cells and Tissue-engineering to Model BBB Function
 
Speakers
  • Prof. Viviana Gradinaru CalTech, USA
    , United States
  • Prof. Feng Shao National Institute of Biological Sciences, China, China
  • Prof. Benoit Vanhollebeke ULB University, Belgium, Belgium

Venue
Parc de Recerca Biomèdica de Barcelona (PRBB)

Parc de Recerca Biomèdica de Barcelona (PRBB), Carrer del Doctor Aiguader, 88, Ciutat Vella, Barcelona, 08003, Spain

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